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Tag: Tuberculous

Antipurified-Protein-Derivative Antibody in Tuberculous Pleural Effusions: DISCUSSION

Only identification of acid-fast bacilli of M tuber­culosis in smear or culture in pleural effusion is completely diagnostic. However, a positive finding is rare, and the culture is time-consuming. Hence, tuberculous pleurisy is one of the major diagnostic problems in pulmonary disease. Nassau et al first applied ELISA to the serodiag- nosis of tuberculosis. Since then, […]

Antipurified-Protein-Derivative Antibody in Tuberculous Pleural Effusions: RESULTS

ODI of Anti-PPD Antibody in Pleural Effusion The mean ODI values of anti-PPD IgG, IgA and IgM antibodies in tuberculous effusions were 0.49±0.19 (mean±SD), 0.72±0.39 and 1.02±0.24. They were significantly higher (p<0.01 in anti-PPD IgG and IgA antibodies, p<0.05 in IgM antibody) than those (0.37±0.11, 0.46±0.27 and 0.86±0.25) in carcinomatous antibodies (IgG in Fig 1, […]

Antipurified-Protein-Derivative Antibody in Tuberculous Pleural Effusions

Сommon etiologies of exudative pleural effusions are tuberculous and carcinomatous. Although the ultimate diagnosis of pleurisy depends on pleural biopsy or cytologic or bacteriologic examination, the diagnostic problem is often great. Since the develop­ment of the ELISA technique in 1972, many authors have attempted to use it to estimate antibodies in serum for diagnosis of […]