In a group of 201 healthy subjects (99 males and 102 females) from a village nearby Milan (unpublished data) the prevalence of hypercalciuria, greater than 300 mg/24 hour in men and 250 mg/24 hour in women, was 12.5% (12% in males and 14% in females). In the same population, considering a 0.15 urinary calcium to creatinine ratio as the upper limit of normal, the prevalence of hypercalciuria was 34% (26% in males and 42% in females), whereas, when the 4 mg/kg/24 hour limit was considered, the rate was 18% (16% in males and 20% in females). The rates of prevalence vary in relation to age and sex (Figg. 1-3), according to the age- and sex-related variations of urinary calcium excretion. In fact, the mean daily urinary calcium and the mean calcium/creatinine ratio were significantly higher in males than in females. The daily calcium output rose over the first two decades and remained constant during adult life in both males and females until the last two decades when it was significantly reduced in both sexes. On the contrary, the highest values of calcium/creatinine ratio were observed in the first decade. The ratio felt over the second decade and it rose again during the third and fourth decades remaining relatively constant until the last decades. The mean calcium/body weight ratio did not differ between males and females and it remained constant with age. Discount drugs online cialis professional online
Figure 1 – Rate of hypercalciuria as mg/24 hour by gender and age.
Figure 2 – Rate of hypercalciuria as Ca/Cr ratio by gender and age.
Figure 3 – Rate of hypercalciuria as mg/kg/24 hour by gender and age.