In the present study, it was observed that vitiligo type appears to be related to repigmentation. Patients with focal type vitiligo achieved better final outcomes with lower cumulative doses and treatment session numbers. Unlike NB-UVB phototherapy and PUVA, targeted phototherapy can selectively treat single vitiliginous patches, spare non- affected areas, and achieve clinical improvements faster. And treatment dosage can be adjusted at each focal patch followed by their previous response. When larger areas are treated using targeted phototherapy, two or three subsequent exposures are required. This observation suggests that focal type vitiligo is better treated by targeted phototherapy.
The possibility of a better response by darker skin types to phototherapy has been suggested. Hadi et al. showed that 53% of patients with skin photo type III or more achieved responses of >75%. On the other hand, no patient with skin photo type I and only 15.6% of patients with skin photo type II achieved this level of repigmentation. In the present study, no significant trend was found between final outcome and skin photo type using the Mantel-Haenszel X2 test (>=0.4387). Most of our patients were of skin photo types III—V, and most were of skin type IV. No patient with type I or II was enrolled. A study with a larger cohort and a mix of racial types should be undertaken to obtain more information on this aspect.
cialis professional online
In the present study, no relationship was established between final outcome and a previous history of treatment. However, in recalcitrant patients longer treatment sessions and higher cumulative doses were needed. We therefore concluded that these patients are suspected to be more difficult to treat with any modalities.
The results of the present study suggest that targeted broadband UVB phototherapy is a valuable option for the treatment of stable vitiligo with focal type of lesions, especially on the face and neck. This induces more rapid repigmentation than traditional NB-UVB at lower cumulative doses. Moreover, this selective treatment of vitiliginous lesions prevented peri-lesional hyperpigmentation, and this treatment reduces the risks of photoaging and skin cancer by sparing non-affected areas.