Hypereosinophilic syndrome

INTRODUCTION

Hypereosinophilic syndrome (HES) represents a heterogenous group of disorders with idiopathic prolonged eosinophilia and evidence of organ in­volvement. Patients determined as HES should fulfill several diagnostic criteria. First, sustained blood eosinophilia at least 1,500/L must be present longer than 6 months. Second, patients must have signs and symptoms of multiorgan involvement. Third, no other apparent causes of eosinophilia must be present, including parasitic or allergic disease or other known causes of peripheral blood eosinophilia.

HES is a multisystem disorder most often affec­ting the heart, lungs, skin, and central and peri­pheral nervous system. Although it has a relatively high frequency, the pathogenesis and natural history ofperipheral neuropathy associated with HES with and without treatment has been poorly defined. cialis super active

In this paper, we report a case of HES in a 16-year-old male, who showed cutaneous and neurologic manifestations initially, and improvement after treatment with corticosteroids.