Fusarium infections do not play a prominent role in human mycoses because Fusarium species are weakly invasive and are considered opportunistic pathogens. Thus, most infections are found in patients with neoplastic or other debilitating diseases maintained by immunosuppressive drugs, or in a severely burned or immunocompromised host. The Fusarium infection’s portals of entry include the respiratory and gastrointestinal tracts, catheter tips and indwelling central venous catheters, and the skin. Infection occurs by direct contact with contaminated soil or plants, inhalation of airborne spores or ingestion of contaminated food.
Infections by Fusarium species in humans can result in localized, focally invasive or disseminated disease. Among immunocompetent individuals, skin lesions typically are localized and develop after skin breakdown at the site of infection. Cutaneous infections in these immunocompetent hosts present most commonly as necrotic lesions that complicate extensive wounds (burns and trauma) and foreign bodies, but to our knowledge no case of cutaneous infection by Fusarium solani in a patient with arteriosclerosis obliterans (ASO) exists in the Korean dermatological literature. Viagra Super Active