A 14-year-old Korean girl presented with hair loss associated with the presence of fine, short and kinky hairs on the scalp which she had had since birth. She had easily-broken, slow-growing hair that seldom required cutting. On physical examination, her scalp hair was noted to be light brown, evenly- pigmented, coarse-textured, and extremely curly (Fig. 1). Her scalp, eyebrows, eyelashes, body hair, nails, and skin were normal in appearance. Two- dimensional color echocardiography and electrocardiography were performed, but abnormal findings were not observed. Her medical history was alsounremarkable.
Fig. 1. Scalp hairs of the 14-year-old patient, the abnormal hairs were light brown, evenly-pigmented, tightly-curled with diffuse hair loss.
No family members had any hair or skin disorder, including alopecia. Histopathologic examination of the scalp revealed the presence of intermediate-sized hair follicles without other abnormalities. Light microscopic examination of clipped hairs from her crown and parietal areas disclosed flattening of the shafts with partial twists at irregular intervals. Her hair index of ovality was 1.5. Scanning electron microscopic examination revealed flattening and irregular twisting of the hair shafts. Weathering of the cuticles was also observed (Fig. 2). These clinical, light and electron microscopic findings were consistent with a diagnosis of woolly hair. canada drugs online
Fig. 2. On scanning electron microscopy the following conditions were observed: (A) weathering of the cuticles (x 317), (B) twisting of the hair shaft (x 200), (C) marked flattening of the hair shaft (x 1010).