Thrombosis Category

We applied our criteria to patients based on data known at the time of the DVT diagnosis. All patients received unfractionated heparin as initial DVT treatment. We assumed that the type and frequency of serious complications would be similar if patients would have received LMWH treatment instead. Our study design allowed us to assess the […]

Our study’s possibly eligible group, whose members each had one relative contraindication to outpatient therapy, had no in-hospital complications. When developing the a priori criteria, we decided to keep the possibly eligible group separate from the eligible group based on a lack of data related to potential outpatient and LMWH therapy in patients with certain […]

This study suggests that objective criteria may be used to select patients for proximal lower extremity DVT home therapy. We showed that complications of bleeding, venous thromboembolism, and death were greater in those patients considered ineligible than in those patients considered eligible for home therapy. The ability of the criteria to identify patients safe for […]

Two patients in the ineligible group had nonfatal symptomatic PE diagnosed by either high-proba-bility ventilation-perfusion scan (one patient) or pulmonary angiogram (one patient) while being treated for the previously diagnosed proximal lower extremity DVT. Both of these patients had adequate anticoagulation at the time of their PE with an activated partial thromboplastin time of > […]

Patients Twelve hundred patients underwent lower extremity duplex ultrasound scanning during the 1-year period (Fig 1). Of these patients, 203 (17%) were diagnosed as having proximal lower extremity DVT, Of the 199 who had inpatient therapy, 195 had charts available for review, constituting our main study cohort. The mean (± SD) age of the study […]

Application of Eligibility Criteria and Determination of Complication Rates By retrospectively applying the a priori eligibility criteria to the study cohort, we classified patients as eligible, possibly eligible, or ineligible for outpatient therapy (Fig 1). Hospital and laboratory records, ventilation-perfusion and pulmonary angiography reports, and autopsy documents were reviewed to see which patients had complications during their […]

Study Setting and Patients Using a computerized registry, we identified all patients who underwent lower extremity duplex ultrasound scanning between July 1, 1993, and June 30, 1994, in the vascular laboratory at Jewish Hospital at the Washington University Medical Center in St. Louis, MO. Patients were selected for chart review if they had been hospitalized […]