Obstructive Sleep Apnea Category

Various oximetric indices have been studied for case finding of OSA, with sensitivities ranging from 40 to 100% and specificities ranging from 39 to 100%. In patients with OSA, we found that minSaO2 and mSa02 were lower, and CT80 higher, than in patients without OSA. Indeed, AHI was negatively correlated with minSa02 and mSa02, and […]

We observed a lower diurnal Pa02 in patients with OSA than in patients without OSA. Because only a small proportion of OSA patients had an associated bronchial obstruction (6/40, 15%), this resting hypoxemia may be in part explained by high BMI. Indeed, several studies conducted in predominantly obese populations found values of Pa02 similar to those of […]

Our data show that in an overweight population, CS, PFTs, and nocturnal oximetry taken alone may not accurately predict the presence or absence of OSA. As shown in Figures 1, 2, there is a considerable overlap between patients with and without OSA, even for variables that independently predict OSA according to logistic regression, and even […]

Multivariate logistic regression analysis showed that sex, CS, FEV1/FEV05, and mSa02 were independent predictors of OSA when computed as categorical variables (Table 4). There was no interaction between sex and other predictive variables. The relationships between AHI and these predictive variables are shown in Figures 1, 2. The parameter estimates calculated by logistic regression when […]

Finally, individual data were analyzed to determine if some ranges or combinations of ranges of variables were highly predictive of either the presence or the absence of OSA. Results are expressed as mean ± SD unless indicated. We considered a p value < 0.05 to be significant. Logistic regression analysis was repeated with an AHI threshold […]

PSG All patients underwent a full-night PSG including two channels of EEG, one channel of electro-oculogram, and one channel of submental electromyogram. Thoracoabdominal movements were recorded with inductance plethysmography. Airflow at the nose and mouth was assessed by a thermistor. All signals were recorded and stored on semiautomated scoring systems (Mini-somno; SEFAM; Nancy, France; or […]

Study Population We analyzed the data from 102 consecutive new overweight patients referred to the respiratory sleep laboratory by the obesity clinic between May 1992 and November 1994. All patients had a body mass index (BMI), calculated as (weight [kg])/(height [m]), of > 25 kg/m2. In each patient, a clinical score (CS) was established and PFTs, […]