Nonspecific Pleuritis Category

It has been suggested previously that pleural biopsy will be a rewarding procedure in patients suspected. of having malignancy or granulomatous pleural disease. However, the reliability of clinical suspicion will vary depending on the expertise of the physician. To facilitate the recognition of patients in whom this procedure is likely to yield a specific diagnosis, […]

Repeat pleural biopsy was a rewarding procedure in those patients whp were ultimately diagnosed to have either malignant or granulomatous pleuritis. The yield of the second pleural biopsy, 55 percent, was actually slightly higher than the 48 percent obtained on the first pleural biopsy. Pleural involvement in both these disorders usually is due to focal […]

The results of the present study are consistent with previous studies indicating that closed needle biopsy of the pleura is a valuable diagnostic technique in the evaluation of the unexplained pleural effusion. However, in contrast to many of these earlier reports, the patients in this study represented a highly selected population. Virtually all of the […]

The 53 patients with nonspecific pleuritis were followed for a mean of 33 (±3) months. Forty-six (87 percent) of these 53 patients were no longer symptomatic and 34 (64 percent) had complete roent-genograhic resolution of their pleural disease. The other 12 asymptomatic patients still had residual pleural thickening and/or small effusions which were markedly improved […]

The reaction to intermediate strength PPD was tested in 22 of the 23 patients with tuberculous granulomatous pleuritis and was positive in 20 (91 percent) of these individuals. Two additional patients with granulomatous pleuritis secondary to blastomycosis and sarcoidosis both had negative PPDs. The frequency of a positive PPD was significantly higher (p<0.001) in the […]

The first pleural biopsy was diagnostic of malignancy or granulomatous pleuritis in 32 (48 percent) of the 66 patients who were ultimately diagnosed to have either of these disorders. Eighty-seven patients had an initial pleural biopsy consistent with nonspecific pleuritis. Pleural tissue was identified in each of these biopsy specimens. Forty-five of the 87 patients […]

The 119 patients had a total of 177 closed pleural biopsies performed. All except two of the patients had a diagnostic thoracocentesis prior to the biopsy and the pleural fluid was exudative by standard criteria (pleural fluid to serum ratio for protein >0.5 and/or LDH ratio >0.6) in all but one of these patients. Forty-one […]