Myocardial Damage Category

Early postoperative ventricular dysfunction, as observed with echocardiography, is more likely to occur because of reversible myocardial stunning during aortic occlusion and reperfusion injury. Creatine kinase (CK) and CKMB are often used with no clear threshold. In this study, it would have been inappropriate to use CK or CKMB, a cytosolic marker, to study the […]

The main findings of our study were that (1) in noncomplicated postoperative CABG, cTnl values remained constantly low, contrasting with very high values when perioperative myocardial infarction occurred, and (2) there was little difference between cTnl, cTnT, and CKMB to diagnose myocardial damage after CABG as assessed by the appearance of new Q wave on […]

Patient Data There were 69 patients without new Q wave (group 1) and 13 with (group 2). Preoperative, operative, and postoperative data are shown in Table 1 for the two groups. No operative death occurred and no mechanical assistance was needed in any patient. There was no significant difference between the two groups as for […]

Blood Sampling Serial venous blood samples were obtained immediately before anesthesia induction, before aortic declamping (0), and 6, 12, 24, and 48 h after aortic declamping. Plasma samples were stored at — 70°C after centrifugation and processed in the month following collection for measurements of CKMB mass, cTnl, and cTnT. Analytical Methods cTnl was measured […]

Cardiac troponin I (cTnl), troponin T (cTnT), and creatine kinase-MB (CKMB mass) are specific markers of myocardial injury and are, at present, widely used to detect perioperative myocardial damage during coronary artery bypass graft (CABG) surgery. They are also of some help to compare different types and routes of delivery of cardioplegia.However, cTnT and CKMB […]