Health Category - Part 4

Concomitant Medications The most commonly used vasoactive drugs were dopamine (94 admissions [44.1%]) and epinephrine (32 [15.0%]), followed by vasopressin (22 [10.3%]) and phenoxy- benzamine (13 [6.1%). Nephrotoxic medications (including aminoglycosides, vancomycin, acyclovir, ganciclovir, ampho- tericin, cidofovir, cyclosporine, tacrolimus, and sirolimus) were used in 58 (27.2%) of the admissions. Anticoagulants and platelet-lowering drugs (unfractionated heparin, […]

A total of 202 potentially eligible patients were identified. Of these, 197 received milrinone in the CCU between January 5 and June 19, 2004; an additional 5 patients who had received milrinone in the operating room but not the CCU were excluded from the study (Figure 1). Of the patients included in the study, 12 […]

Descriptive data were summarized as means, standard devi­ations, and medians for continuous variables and proportions for categorical variables. Univariate analysis between categorical independent variables and each outcome was performed by means of 2 x 2 contingency tables. Variables having statistically significant correlation with the outcomes (p < 0.05) according to the Fisher exact test were […]

A retrospective evaluation was performed in a cohort of consecutive patients. Patients admitted to the pediatric Critical Care Unit (CCU) ofThe Hospital for Sick Children starting in January 2004 who received milrinone intravenously were eligible for inclusion. There were no exclusion criteria, which allowed patients with a variety of indications to be included in the […]

INTRODUCTION Milrinone is a potent selective inhibitor of type III phosphodiesterase. It is used to improve cardiac output by inotropic effect and reduction of afterload. In addition, milrinone may improve myocardial relaxation between contractions. Milrinone is used as a first-line agent for children who have undergone cardiac surgery for prevention of low cardiac output syndrome […]

In considering the recall section, participants stated that asking patients to describe their medications is an important aspect of the SMAT. Indeed, patients who understand their disease, the need for treatment, and the role of their medications are generally more likely to adhere to medication regimens. Evidence is also available that the ability to recall […]

Interviews and a questionnaire were used to evaluate the face validity of the SMAT, an instrument that incorporates evidence-based components to determine functional, cognitive, and recall capabilities, as well as self-reported adherence and purposeful nonadherence. The study presented here is the first phase of a larger project, the second phase of which involved determining the […]