Drug Category

Diabetes, use of enteral feeding, cancer, inflammatory bowel disease, gastrointestinal surgery, and previous residence or care in an institution were not associated with the development of CDAD. Furthermore, an analysis to determine if the total number of risk factors per patient affected development of CDAD revealed no such influence (see Figure 1).

In this outbreak study, current use of PPIs was not associated with the development of hospital-acquired CDAD. In both the case and control groups, a total of 69 patients had received a PPI during the study period. All patients in the case group who were receiving a PPI were also receiving an antibiotic at the […]

Spotentially eligible patients identified from the Infection Prevention and Control reports were not included because they had undergone cancer chemotherapy in the preceding 8 weeks. The case patients were then matched to controls according to the previously stated criteria. Eight case patients were excluded at this stage because matched controls could not be found: 4 […]

Dichotomous data were collected for both groups regarding use of PPIs, use of antibiotics within the 30 days preceding diagnosis of the CDAD infection, diagnosis of diabetes mellitus, use of enteral feeding within the 30 days preceding the infection, diagnosis of cancer, previous gastrointestinal surgery, diagnosis of inflammatory bowel disease, and previous residence or care […]

The Trillium Health Centre, located in Mississauga, Ontario, serves more than 1 million residents in the Peel Region. At the time of the study reported here, this hospital had 794 acute, rehabilitation, and chronic care beds. An outbreak of CDAD was declared on February 28, 2007, after evidence of transmission among patients and an increase […]

INTRODUCTION Clostridium difficile is an anaerobic, gram-positive, spore-forming, rod-shaped bacterium commonly respon­sible for hospital-acquired enteric infections. It is associated with substantial morbidity and mortality. Clostridium difficile—associated disease (CDAD) is defined as 3 or more loose, watery stools within a 24-h period that are unusual or different for the patient, without any other identifiable cause. The […]

It was theorized that specific patient factors might have influenced a surgeon to use ABC in a particular orthopedic case, if it was perceived that the patient was at increased risk of infection or if there was potential for healing to be prolonged. Whether a patient had refrained from smoking tobacco was considered because the […]