Apoptosis Category

Placental vasculogenesis is a process of de novo vascular formation involving molecular and morphological differentiation processes that lead to the development of tertiary villi from secondary villi. It is widely accepted that pluripotent mesenchymal cells are the source of cells that participate in vasculogenesis. Thereafter, these differentiated, multipotent vasculogenic cells initiate the first placental angiogenesis […]

Determination of Vasculogenic Stages Using semithin sections and CD31 immunohistochemistry, vasculogenic and angiogenic areas were determined and classified as described previously. Development and recruitment of hemangioblastic progenitor cells, formation of hemangioblastic cell cords, differentiation of primitive endothelium, formation of primitive lumen, endothelial tube elongation, and angiogenic branching were determined. In mesenchymal villi, islands of hemangioblastic […]

Tissue Collection Human placental tissues from the first trimester (n = 15 total from 22, 24, 26, 27, 29, 32, 36, 40, 42, 48, and 52 dpc) were collected from clinically normal pregnancies, which were terminated voluntarily by dilation and curettage. The distribution of the number of samples according to dpc was two samples each […]

Apoptosis is a process of programmed cell death and is regulated by various proteins, including membrane-associated proteins, such as Fas (CD95), Fas ligand (CD95L), tumor necrosis factor (TNF) a, and TNF receptor, and cytoplasmic/nuclear proteins, such as Bcl-2, Bak, Bax, and caspases. Apoptosis takes part in both embryonic tissue morphogenesis and adult tissue regulation by […]