An interesting observation was also made during running where atrioventricular blocks seemed to develop (Figure 7). This occurred on many occasions but not every day for any particular hamster. It occurred mostly when heart rate at rest was above 370 beats/min.  Results are given in Table 1. RR variability changed from day to day in a single hamster (eg, 2.7% to 29.3% for hamster # 8).The running cardiomyopathic hamster with continuous telemetric ECG: A new heart failure model to evaluate 'symptoms'

Figure 7 Electrocardiogram of a cardiomyopathic hamster taken at 16:01 h (at rest) when the heart rate was 394 beats/min (left), and later the same day, at 20:01 h (during running) when heart rate was 317 beats/min (right). An atrioventricular block was suspected  You can be sure this pharmacy will offer the finest quality drugs you need, so buying Xopenex Inhaler Dosage will always be safe and very pleasant for you as a customer and patient.

TABLE 1 Heart rate measured at rest on four consecutive days in 11 cardiomyopathic hamsters aged 218 to 220 days

Hamster Day RR (s) N HR (beats/min) Mean HR (beats/min) CV (%)
1 1 0.1877±0.00349 77 320 307.5±14.2 4.6
2 0.1928±0.01483 96 311
3 0.2091±0.04837 182 287
4 0.1926±0.01354 198 312
2 1 0.1612±0.00289 137 372 347.5±16.7 4.8
2 0.1793±0.00467 212 335
3 0.1750±0.00486 217 343
4 0.1763±0.00220 216 340
3 1 0.1951±0.01291 195 307 311.3+21.0 6.8
2 0.1842±0.01553 207 326
3 0.1824±0.02194 209 329
4 0.2117±0.02245 179 283
4 1 0.1795±0.01272 212 334 313.3+29.5 9.4
2 0.1792±0.01469 212 335
3 0.2208±0.04933 172 272
4 0.1923±0.01481 192 312
5 1 0.2044±0.01367 182 294 343.3+34.5 10.1
2 0.1662±0.01167 152 361
3 0.1614±0.01040 184 372
4 0.1733±0.01888 145 346
6 1 0.1724±0.00296 221 348 310.8+34.0 10.9
2 0.1824±0.01429 198 329
3 0.2200±0.03286 171 273
4 0.2048±0.02316 186 293
7 1 0.1889±0.01429 196 318 314.0+38.4 12.2
2 0.1803±0.00925 179 333
3 0.2313±0.01906 123 259
4 0.1736±0.00735 213 346
8 1 0.1974±0.00540 193 304 262.5+32.3 12.3
2 0.2552±0.07467 107 235
3 0.2515±0.06148 151 239
4 0.2210±0.01435 119 272
9 1 0.1522±0.00296 251 394 337.0+51.5 15.3
2 0.2071 ±0.03096 161 290
3 0.2019±0.01016 188 297
4 0.1634±0.00836 223 367
10 1 0.1864±0.01484 165 322 296.3+64.9 21.9
2 0.2405±0.07314 157 249
3 0.2521±0.04777 67 238
4 0.1596±0.01433 239 376
11 1 0.1855±0.01124 205 324 276.0+73.7 26.7
2 0.1798±0.01157 209 334
3 0.3472±0.13400 109 173
4 0.2202±0.04674 169 273

CV Coefficient of variation; IIRI Icart rate; N Number of RR intervals measured; RR Interval between two R waves as determined from electrocardiograms