To families of asthmatic patients, high incidence of atopic diseases, abnormal exercise-induced bronchial lability, and impaired ventilatory (unctions are known to be present. Increased bronchial sensitivity to bronchoconstrictor agents has been reported in families of asthmatic patients and patients with chronic obstructive pulmonary disease, and the occurrence of late-onset asthma is common, especially in patients with a history of allergic rhinitis and/or sinusitis.
The aim of the present study was to determine the bronchial hyperreactivity (BHR) to methacholine in “healthy” children of asthmatic families, and compare it with the BHR in “healthy” parents of asthmatic children. The effect of cromolyn sodium on the nonspecific airway hyperreactivity in these children was examined as well. buy viagra jelly